Dejan Kulusevski will return to Tottenham's matchday squad for the first time in 526 days for Monday's visit of Coventry, but Sávio and Lucas Bergvall will be absent.
Spurs have spent the majority of this week in a warm weather training camp in Marbella, but Savio was absent after he reported a "muscular problem" on Tuesday and Bergvall is sidelined for "two weeks" with a knee issue.
Those absences along with Kulusevski's ever-improving fitness have opened the door for the Swedish playmaker to potentially play on Monday night after a serious knee injury has sidelined the attacker since the end of the 2024-25 season.
"Yes, Kulusevski on the bench. We had a meeting with the medical staff. They gave the OK and it's great news. I think it's one of the best news after Everton game last season because Deki he suffered too much. He deserves to feel emotion on the pitch," boss Roberto De Zerbi told a news conference.
Dejan Kulusevski is set to return after a long absence. Photo by Alex Pantling/Getty Images. "Unfortunately Savio on Tuesday... before we leave for Marbella, he felt a muscular problem. We lost him for some weeks unfortunately.
"And Lucas Bergvall because he had a problem at the beginning of the game in Manchester.
"The day after Manchester [United], Sunday, he came to [the] training ground to our medical staff. And I think two weeks [out]."
De Zerbi provided a positive update on right-back Pedro Porro, who could be available for the trip to Chelsea next Saturday.
However, bottom-of-the-table Spurs will be missing seven players for the clash with Coventry with Rodrigo Bentancur suspended for a fixture where the hosts will be desperate to end a six-match winless start to the new Premier League campaign.
"Coventry is a good team. They played a fantastic Championship last season," De Zerbi said.
"But we are Tottenham, keeping humility, keeping what you want, but we want to show to be good enough to win the games, especially if we deserve to win the games."
Kulusevski could be required to help Spurs get off the mark in the league after a torrid spell on the sidelines with a patella injury, which required a second procedure in March to fix the long-standing problem.
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