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The Commanders take on the 49ers for a Monday night showdown. Can San Francisco go 6-0?
Here's what to know about the Week 6 matchup.
When is the game?
The game airs at 8:15 p.m. ET on ESPN.
How can fans watch?
New music for 'Monday Night Football'
ESPN and Apple Music will collaborate on music curation for "Monday Night Football" games throughout the 2026 NFL season.