Arthur Fery beat James Duckworth at the Cincinnati Open in his first match since his memorable run to the Wimbledon semi-finals.
The 24-year-old won 6-4 2-6 7-6 (4) in two hours and 34 minutes.
Fery arrived in Ohio ranked 36 in the world, a meteoric rise having been outside the top 150 at the start of the grass-court season and 114th going into Wimbledon as a wild card.
The right-hander took some time off after what he admitted was a "life-changing fortnight", before undertaking a training block at the National Tennis Centre in Roehampton.
Seeded 32nd at only his second Masters 1000 event - and the first he has entered directly through ranking - Fery broke Australian veteran Duckworth in the first game, only for a couple of foot faults to cost him in the next.
He snatched a second break with a backhand passing shot for 5-4 on his way to the first set.
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But Duckworth, the world number 86, began the second set strongly by winning the first three games and broke Fery's serve again at 5-2 to level the match.
Fery failed to convert the only break point of a tense third set, but won four straight points in the tie break to seal his progress to face another Australian, fifth seed Alex De Minaur, in the next round.
In the WTA draw, Britain's Katie Boulter was beaten 6-3 6-3 by Wimbledon champion Linda Noskova.